@Article{HurtadoWQMCTDSMHTT:2020:SiPrOb,
author = "Hurtado, Carolina Ramos and Wachesk, Cristiane da Costa and
Queiroz, Rafaela Campos and Macedo, Erenilda Ferreira de and
Correia, Rebeca Falc{\~a}o Borja de Oliveira and Taiariol,
Thalita Sani and Diniz, Milton Faria and Santos, Alexandre Martins
Isaias dos and Montanheiro, Thais Larissa do Amaral and Hurtado,
Gabriela Ramos and Trava-Airoldi, Vladimir Jesus and Tada, Dayane
Batista",
affiliation = "{Universidade Federal de S{\~a}o Paulo (UNIFESP)} and
{Universidade Federal de S{\~a}o Paulo (UNIFESP)} and
{Universidade Federal de S{\~a}o Paulo (UNIFESP)} and
{Universidade Federal de S{\~a}o Paulo (UNIFESP)} and {Instituto
Nacional de Pesquisas Espaciais (INPE)} and {Instituto Nacional de
Pesquisas Espaciais (INPE)} and {Instituto de Aeron{\'a}utica e
Espa{\c{c}}o (IAE)} and {Universidade Federal de S{\~a}o Paulo
(UNIFESP)} and {Instituto Tecnol{\'o}gico de Aeron{\'a}utica
(ITA)} and {Universidade Estadual Paulista (UNESP)} and {Instituto
Nacional de Pesquisas Espaciais (INPE)} and {Universidade Federal
de S{\~a}o Paulo (UNIFESP)}",
title = "A simple procedure to obtain nanodiamonds from leftover of HFCVD
system for biological application",
journal = "SN Applied Sciences",
year = "2020",
volume = "2",
number = "352",
pages = "2",
keywords = "Nanodiamonds · Ultrasonic cavitation · CVD diamond ·
Functionalization · Cytotoxicity · Colloidal suspension.",
abstract = "Nanodiamonds (NDs) are amongst the most investigated carbon-based
nanostructures due to their chemical stability and favorable
mechanical properties. Despite the number of works on methods for
NDs production, one of the main challenges is to achieve their
colloidal stability in aqueous suspension. Additionally, NDs are
normally obtained by expensive, complex and time-consuming
process. Herein, it was presented a facile method to obtain NDs in
aqueous suspension by using columnar structure diamond from
Hot-Filament Chemical Vapour Deposition reactor (HFCVD). CVD
diamond leftover thick flm from CVDVale Company was used.
Therefore, this method has the advantage of being not only
practical but also cost-efective since it brings a proftable use
of CVD diamond leftover. The Diamond thick flm was submitted to
ultrasonic cavitation in the presence and absence of ZrO2
microbeads in aqueous medium. The NDs hydrodynamic diameter and
the stability in aqueous suspension were monitored by light
scattering, size and morphology were analyzed by transmission
electronic microscopy. Considering the wide application of NDs in
biomedical devices, cytotoxicity of aqueous suspensions of NDs was
evaluated against murine embryonic fbroblast cells. Furthermore,
NDs were functionalized with hydrogen and carboxyl groups. NDs
aqueous suspension of straight size distribution was obtained even
in the absence of ZrO2 beads, indicating that they may be
dispensable in order to decrease NDs size. NDs of average
hydrodynamic diameter of 22 nm and \−35 mV of
Zeta-potential were obtained after ultrasonic cavitation followed
by 2 h of centrifugation, not demonstrating cytotoxicity to cells
at very low (0.050.5 \μg/mL) nor at higher concentrations
(116 \μg/mL). Nevertheless, NDs showed a moderate
cytotoxicity at intermediary concentration range (0.52.2
\μg/mL). From our knowledge, this is the frst work that
reports on a facile method for providing NDs aqueous suspension
with high colloidal stability from HFCVD diamond leftover.",
doi = "10.1007/s42452-020-1967-1",
url = "http://dx.doi.org/10.1007/s42452-020-1967-1",
issn = "2523-3963",
label = "lattes: 3455204481678421 11 HurtadoWQMFTDSMHAT:2020:SiPrOb",
language = "pt",
targetfile = "hurtado_simple.pdf",
urlaccessdate = "28 mar. 2024"
}